Original Model Status

Model curated, but did not run in PCEnv simulator. Documentation was also non-existent.

Work done on model:

Read the publication titled 'Hyperelastic modelling of arterial layers with distributed collagen fibre orientations' by Gasser et. al., and wrote the documentation from scratch. Also managed to locate an online pdf version of the article and included this link in the documentation along with its PUBMED ID. Seeing as the model was tagged under the 'Mechanical constitutive Laws' section, it was decided to also include a link to a page regarding the implementation of CellML files in CMISS (maintained by David Nickerson of the Bioengineering Institute, University of Auckland).

Also, this model had a total of 3 variants; each variant correpsonding to a different functional form of the 'fibre dispersion law' presented in the publication by Gasser et. al.

The model file associated with version b (presented here) focuses on the functional form of the fibre dispersion law corresponding to the the combination 1,2,4,8 (FiberDispersion_law_1248), with 1 and 2 representing the isotropic components of the functional form, and 4 and 8 representing the anisotropic components of the fucntional form.

Curation Status:

Model still does not run in PCEnv simulator, as it (PCEnv) cannot handle matrices and these mechanical laws involve the use of many transformation matrices. We have also not discerned whether or not it runs smoothly in CMISS, but the common notion is that it does, seeing as many people within the Institute utilize the CellML files of models tagged under the 'Mechanical Constitutive Laws' section. The model now has sufficient documentation and variants are clearly laid out.

Further work required:

Curate the model to an extent where it may one day run in PCEnv, this is dependant on when PCEnv will be able to integrate matrix functionality. Confirm that it works in CMISS.